The Zantac lawsuits claim that Zantac can be contaminated with the cancer-causing substance N-nitrosodimethylamine (NDMA).
Our law firm is accepting clients who took Zantac and have been diagnosed with cancer. We have been handling lawsuits against drug companies since 1955. We are listed in Best Lawyers in America and The National Trial Lawyers Hall of Fame.
What Do We Know About the Zantac Lawsuits?
On September 13, 2019, the U.S. Food and Drug Administration (FDA) reported the discovery of the carcinogenic contaminant N-nitrosodimethylamine (NDMA) in Zantac (ranitidine), a common heartburn medication available in both prescription and over-the-counter versions.
In April of 2020, the FDA announced that all Zantac brand heartburn drugs, prescription and over-the-counter, should be immediately pulled from the market because of potential NDMA contamination, a chemical linked to cancer.
The first Zantac lawsuit was filed in California on 2019. In that lawsuit, the plaintiffs accuse drugmakers Sanofi and Boerhringer Ingelheim of manufacturing, marketing, and selling a product they knew or should have known had been contaminated with an industrial chemical known to cause cancer.
The exact cause of the NDMA contamination is still under investigation. However, during the period in which Boerhinger Ingelheim and Sanofi manufactured and marketed Zantac, scientific research demonstrated a clear link between ranitidine, the active ingredient in Zantac, and NDMA. Specifically, when ranitidine comes in contact with water, it creates a chemical reaction that causes the formation of NDMA.
Despite the availability of this information, the drugmakers chose not to disclose this risk to the government or to consumers.
What Injuries & Side Effects Result from Zantac and NDMA?
In addition to causing cancer, NDMA is a potent hepatotoxin. Short-term exposure to NDMA can cause liver damage (such as liver fibrosis and scarring). Long-term exposure can increase the risk of liver, kidney, and lung tumors.
Symptoms of NDMA overexposure include headaches; fever; nausea; jaundice; vomiting; abdominal cramps; enlarged liver; reduced function of the liver, kidneys and lungs; and dizziness.
Other adverse effects that have been associated with Zantac include:
- nervous system disorders
- arrhythmia or tachycardia (irregular or rapid heartbeat)
- vitamin B-12 deficiency
- hepatitis, liver failure, and jaundice
- increased risk of pneumonia
- low platelet levels in the blood
- skin rashes and hair loss
What Do We Know About NDMA?
NDMA is used in aviation and rocket fuel and industrial lubricants. It is also a by-product of several industrial processes, including gasoline refining and the treatment of wastewater containing nitrogen.
Other applications for NDMA include inducing carcinogenesis in laboratory rats for cancer research. NDMA may also be found in a number of food products, such as cured meats, and is an ingredient in tobacco fumes. Fortunately, NDMA does not appear to accumulate in tissues.
Under the federal Emergency Planning and Community Right-to-Know Act of 1986 (EPCRA), NDMA is classified as “extremely hazardous.” Because of this, there are stringent reporting requirements for companies and individuals who produce, store, or use the substance in large amounts.
What Compensation is Recoverable in Zantac Lawsuits?
If you took Zantac and have been diagnosed with cancer, then we will be seeking the following damages for you:
- Past and future medical expenses that result from the injuries.
- Past and future pain and suffering (physical and mental) caused by the injuries, and the treatment and recovery process.
- Past and future wage loss.
- Past and future loss of earning capacity.
- Past and future loss of enjoyment of life.
- Punitive damages, if appropriate.
Have there been Financial Settlements Involving Zantac?
As of this time, there have been no large groups of mass tort settlements involving Zantac and the potential link to bladder or stomach cancer. Generally, however, large groups of settlements do not occur until such time as a few lawsuits are tried before a jury, and the manufacturer is able to more thoroughly understand its financial risk.
In February 2020, an MDL was established for Zantac in federal court in Florida. Our law firm is serving on the Plaintiffs' Steering Committee and as head of the Science Committee in the MDL. As of February 17, 2021, more than 500 lawsuits were pending in the MDL.
Attorneys Mike Papantonio & Sara Papantonio discuss the Zantac Lawsuits
FDA Studies and Recalls Regarding Zantac
On April 1, 2020, The U.S. Food and Drug Administration (FDA) announced its request that all Zantac brand heartburn drugs, prescription and over-the-counter, be immediately pulled from the market.
This action came after the FDA’s ongoing investigation, which concluded that storing this drug at “higher-than-normal temperatures” elevates levels of a probable human carcinogen within the drugs. The federal agency determined that, because there is no way to know how the drugs currently in the market are being stored, their presence and use poses a “risk to public health.”
Zantac Lawsuit News
Statement alerting patients and health care professionals of NDMA found in samples of ranitidine
The FDA has learned that some ranitidine medicines, including Zantac, contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA) at low levels. NDMA is classified as a probable human carcinogen (a substance that could cause cancer) based on results from laboratory tests. To read more, click FDA Communication
Company Halts Ranitidine Production Over NDMA Contamination Concerns
Novartis's Sandoz unit has announced that they are halting distribution of generic ranitidine (Zantac), after some lots of ranitidine were found to contain small amounts of N-nitrosodimethylamine (NDMA). To read more, click Pharmacy Times
Heartburn Drug Found to Contain Traces of Cancer-Causing Chemical
U.S. health officials have found low levels of a potentially cancer-causing chemical in a popular heartburn drug. To read more, click Live Science