The FDA has issued a warning about the migraine and epilepsy drug Topamax due to its increased risk of causing birth defects. Recently released data shows that women taking the drug Topamax while pregnant were 21 times more likely to give birth to a child with cleft palate deformities or cleft lips. Other child birth defects have been linked to Topamax like limb malformations, genital birth defects, spina bifida, craniofacial defects, hypospadias, neural tube defects, lung and heart defects.
FDA Strengthens Topamax Warning On Birth Defects Data
WSJ March 4, 2011
The U.S. Food and Drug Administration is strengthening warnings on topiramate, an antiseizure drug that is also used to prevent migraines, because new data suggest an increased risk of birth defects when used during pregnancy.
Women Warned About Epilepsy Drug
NYT March 4, 2011
The Food and Drug Administration warned women of child-bearing age that the epilepsy drug Topamax can increase the risk of birth defects around the mouth.