Fosamax Lawsuit
Levin, Papantonio shareholder Tim O'Brien informs the Fosamax Examiner that closing arguments are set for Tuesday, April 17, in the New Jersey Fosamax bellwether trial in the case of Jo Ann Sessner vs. Merck & Co.. The case involves the claim of a Florida Fosamax patient who developed Stage 3 bisphosphonate-related osteonecrosis of the jaw after more than six years of Fosamax use. Read More
In The News
A New England Journal of Medicine study recently published indicates that less than 10% of women with normal, mild, or moderate T-scores will develop osteoporosis over a fifteen year period. This study calls into question the currently Medicare DEXA-scan screening protocol of every two years for postmenopausal women. Further, because most osteopenic women never would develop osteoporosis, the study refutes marketing positions adopted by Merck & Co. relating to its prescription drug Fosamax which Merck touted would help osteopenic women prevent osteoporosis. Read More
In September 2011, Chief Judge Garrett Brown of the United States District Court for the District of New Jersey announced his upcoming retirement from the federal bench. Chief Judge Brown was the judge assigned by the Judicial Panel on Multidistrict Litigation ("JPML") to oversee the Fosamax Femur MDL pending in the District of New Jersey. As a result of Judge Brown's announced retirement, the JPML reassigned the Fosamax Femur MDL to District Judge Joel Pisano, effective November 22, 2011. Like Chief Judge Brown, Judge Pisano sits in Trenton, NJ.&nb Read More
The Wall Street Journal reports that Merck & Co. has been issued a criminal investigation subpoena by the U.S. Department of Justice regarding how Merck marketed its brain tumor medication, Temodar; its hepatitis C drug, PegIntron; and its cancer treatment, Intron A. In an August 2011 filing with the Securities and Exchange Commission, Merck disclosed the subpoena as part of a “federal health-care investigation under criminal statutes”. Read More
ADELPHI, MD
At today's FDA Panel conference on the long term use of osteoporosis drugs like Fosamax, presenter Arthur C. Santora MD, PhD, speaking for Merck, the drug manufacturer, attempted to convince the panel that limits on the duration of the drugs use were not necessary. However, Dr. Santora did admit that drug "holiday" (meaning a temporary interruption in usage) may be considered for patients who are no longer considered to have a sufficiently high fracture risk. Read More
ADELPHI, MD
In the early morning session of today's FDA Panel conference on the long term use of bisphosphonates, like the drug Fosamax, the FDA's Lead Medical Officer Fatmatta Kuyateh, M.D. indicated that radiographic findings consistent with atypical femur fractures case have been associated with bisphosphonate use. Read More
A review of Merck's public filings reveals that Merck has spent more than $150 million litigating approximately 1,500 cases involving Fosamax patients who developed bisphosphonate-related osteonecrosis of the jaw after taking Fosamax. This figure is certainly striking given the relatively small number of cases in litigation and given the fact that, of the 1,500 cases, Merck has only done active discovery in less than 50 of the cases. Read More
Fosamax has long been known to have an incredibly long terminal half-life in bone. Merck, the manufacturer of Fosamax, has conducted clinical trials which show that the the half-life of Fosamax in bone is 10.9 years. Despite Fosamax's well established long half-life in bone, Merck insists that the biologic effects of Fosamax quickly dissipate after the last pill is taken. Recently published research, however, shows that Merck's claim of "no lingering effect" is unfounded. In the July 2011 edition of the medical journal BONE, meta Read More
The International and American Association for Dental Research has published a major prevalence study and a major case control study showing that the use of oral bisphosphonate drugs such as Fosamax massively increases a patient's relative risk for the development of osteonecrosis of the jaw (literally, "death of the jaw bone"). Published in the Journal of Dental Research April 2011 edition, the article "Risk Factors for Osteonecrosis of the Jaws: a Case-Control Study" shows that Fosamax patients had an odds ratio of 12.2 for the develo Read More
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